Nitrate level (μmol/l) | Groups | 0 day | 4th day | 8th day | 12th day | 16th day |
---|---|---|---|---|---|---|
 | Normal | 19.24 ± 0.31 | 19.91 ± 0.28 | 19.58 ± 0.42 | 19. 73 ± 0.34 | 19.92 ± 0.49 |
 | Sham | 20. 79 ± 0.39 | 19.57 ± 0.36 | 19.87 ± 0.47 | 19.62 ± 0.32 | 19.35 ± 0.27 |
 | I/R | 20.16 ± 0.26 | 31.43 ± 1.12a | 36.27 ± 1.08a | 31.27 ± 0.79a | 29.82 ± 0. 74a |
 | Vehicle | 20.36 ± 0.39 | 31.26 ± 1.13a | 38.16 ± 1.09a | 32.53 ± 0.83a | 28.93 ± 0.59a |
 | Tacrolimus (1) | 20.97 ± 0.28 | 36.67 ± 1.38a | 42.94 ± 1.46a | 37.39 ± 0.83a | 34.69 ± 1.25a |
 | Tacrolimus (2) | 20.62 ± 0.64 | 43.78 ± 0.64b | 49.38 ± 0.46b | 44.67 ± 0.46b | 41.67 ± 0.32b |
 | Tacrolimus (3) | 20.09 ± 0.42 | 49.59 ± 0.54b | 57.35 ± 0.36b | 54.56 ± 0.78b | 51. 74 ± 0.34b |
MDA level (nmol/l) | Normal | 0.81 ± 0.32 | 0.83 ± 0.46 | 0. 79 ± 0.31 | 0.82 ± 0.36 | 0.83 ± 0.43 |
 | Sham | 0.82 ± 0.46 | 0.81 ± 0.32 | 0.83 ± 0.31 | 0.81 ± 0.34 | 0.85 ± 0.39 |
 | I/R | 0.74 ± 0.39 | 18.94 ± 1.74a | 24.54 ± 1.56a | 18.31 ± 1.58a | 16.42 ± 2.23a |
 | Vehicle | 0.86 ± 0.23 | 18.61 ± 1.34a | 25.59 ± 1.61a | 17.39 ± 1.57a | 17.14 ± 2.01a |
 | Tacrolimus (1) | 0.82 ± 0.38 | 26.43 ± 1.58a | 33.43 ± 1.67a | 28.81 ± 1.58a | 26. 74 ± 1.32a |
 | Tacrolimus (2) | 0.84 ± 0.36 | 40.36 ± 1.34b | 44.61 ± 1.25b | 37.67 ± 1.46b | 34.38 ± 1.52b |
 | Tacrolimus (3) | 0.81 ± 0.29 | 49.71 ± 1.45b | 56.36 ± 1.54b | 49.69 ± 1.39b | 46.41 ± 1.23b |