Figure 2
From: GAP-43 expression correlates with spinal motoneuron regeneration following root avulsion
Representative photomicrographs showing regenerative axons at reimplantation area and root at 3 days (large arrows in A and B) and the C7 spinal nerve at 2 weeks (C, D) post-injury in the neonatal (A, C) and adult (B, D). No GAP-43-IR regenerative axons were found in the reimplanted area (A) and the C7 spinal nerve (C) following root avulsion and reimplantation in the neonatal. Numerous GAP-43-IR regenerative motor axons were found in the reimplanted area (B) and the C7 spinal nerve (D) following root avulsion and reimplantation in the adult. Insertion in B is the enlargement of the rectangle area in B showing GAP-43 positive fibers grow into the re-implanted root (small arrows). Scale bar = 100 μm.