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Figure 4 | Journal of Brachial Plexus and Peripheral Nerve Injury

Figure 4

From: Functional cooperation of of IL-1β and RGS4 in the brachial plexus avulsion mediated brain reorganization

Figure 4

Modulation of RGS4 membrane distribution in cultured neuron. Cortical neurons were grown for 10 days, then RGS4 subcellular distribution in the presence or absence of db cAMP, KT5720 (A); IL-1β, IL-1ra (B) was assayed by Western blotting. The localization of PKCβ within lipid rafts microdomain was assayed by discontinuous sucrose centrifugation and Western blotting (C). IL-6 content in the presence or absence of IL-1β, IL-1ra was evaluated by ELISA assay (D). The results were normalized against vehicle treated neurons. Statistical differences were evaluated by ANOVA analysis.*p < 0.05 vs control.

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Journal of Brachial Plexus and Peripheral Nerve Injury

ISSN: 1749-7221