Figure 4From: Reconstruction of sciatic nerve after traumatic injury in humans - factors influencing outcome as related to neurobiological knowledge from animal research Schematic drawing of a sciatic nerve at mid-thigh level with the potential factors that influence functional outcome extending from local signal transduction mechanisms in Schwann cells and neurons, secondary changes in the target areas, apoptosis of neurons in e.g. dorsal root ganglia, and reorganization at the cortical and subcortical levels. Back to article page