Figure 7
From: A new cervical nerve root avulsion model using a posterior extra-vertebral approach in rats
Immunohistochemical findings. Immunohistochemistry for Iba1 (A, D), ED-1 (B, E), GFAP (C, F) in the ventral horn. Representative sections are shown from sham group (A, B, C) and extra-vertebral avulsion group at day 28 (D, E, F). Arrowheads indicate immunopositive cells. (Bar: 100 μm.) G, H, I: Results of quantitative evaluation of immunostaining are summarized in a bar graph (G: Iba1, H:ED-1, I:GFAP). The number of Iba1- and GFAP-positive cells at day 14 and ED-1- and GFAP-positive cells at day 28 significantly increased compared with sham and unlesioned side (*P < 0.001). The number of Iba1-positive cells at day 14 significantly increased compared with at day 28 (†P < 0.001). The number of ED-1- and GFAP-positive cells significantly increased at day 28 compared with at day14 (§P < 0.001).